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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sáenz, Ramiro | CF | Yomiuri Giants | 31 | 07/04/2013 | Philadelphia | USA | Left | Left | 6' 1" | 210 lbs | $168,000 |
| Saikawa, Atsushi | SP | Hanshin Tigers | 30 | 05/03/2014 | Kaizuka | JPN | Right | Right | 6' 5" | 235 lbs | $1,900,000 |
| Sakai, Norihisa | SS | Orix Buffaloes | 22 | 04/23/2022 | Nara | JPN | Right | Right | 6' 0" | 180 lbs | $100,000 |
| Sakamoto, Senzo | C | Orix Buffaloes | 33 | 05/19/2011 | Hashima | JPN | Right | Right | 6' 3" | 250 lbs | - |
| Sakamoto, Tsutomu | C | Fukuoka Hawks | 32 | 04/16/2012 | Sabae | JPN | Right | Right | 5' 10" | 210 lbs | - |
| Sakamoto, Yuji | MR | Chiba Marines | 27 | 04/08/2017 | Kawachinagano | JPN | Left | Right | 6' 2" | 205 lbs | $100,000 |
| Sakei, Yoshitoki | SP | Orix Buffaloes | 24 | 10/10/2020 | Yokohama | JPN | Left | Left | 6' 4" | 205 lbs | - |
| Sakuma, Katai | CF | Chunichi Dragons | 27 | 07/13/2017 | Yokohama | JPN | Right | Right | 6' 1" | 215 lbs | - |
| Sakuma, Yoshihide | SS | Hanshin Tigers | 27 | 07/16/2017 | Tokyo | JPN | Right | Right | 5' 10" | 195 lbs | $100,000 |
| Saludar, Rommel | SS | Chunichi Dragons | 18 | 06/27/2026 | Tagapua | PHI | Right | Right | 5' 10" | 170 lbs | - |
| Sánchez, Orlando | C | Chiba Marines | 27 | 09/02/2017 | Pedro Betancourt | CUB | Switch | Right | 5' 11" | 205 lbs | $464,000 |
| Santos, Carlos | MR | Hanshin Tigers | 31 | 01/22/2013 | Iowa City | USA | Right | Right | 6' 3" | 230 lbs | - |
| Sanu, Yasuhide | SP | Yokohama BayStars | 21 | 01/21/2023 | Sano | JPN | Right | Right | 6' 0" | 190 lbs | - |
| Sasaki, Rikiya | SP | Saitama Lions | 20 | 11/22/2023 | Ishikawa | JPN | Right | Right | 6' 0" | 180 lbs | - |
| Sato, Hitoshi | 2B | Yokohama BayStars | 39 | 12/21/2004 | Owase | JPN | Right | Right | 6' 1" | 180 lbs | $600,000 |
| Sato, Kiyohira | CF | Yomiuri Giants | 23 | 03/09/2021 | Tokyo | JPN | Switch | Right | 6' 1" | 190 lbs | $100,000 |
| Sato, Naganori | LF | Fukuoka Hawks | 32 | 12/11/2011 | Kumamoto | JPN | Left | Left | 6' 4" | 205 lbs | $5,070,000 |
| Sato, Takanibu | SP | Orix Buffaloes | 25 | 04/08/2019 | Hadano | JPN | Right | Right | 6' 0" | 210 lbs | $480,000 |
| Sato, Yodo | SP | Orix Buffaloes | 24 | 02/05/2020 | Kawasaki | JPN | Left | Left | 6' 3" | 215 lbs | $1,200,000 |
| Sato, Yoshinori | 2B | Chiba Marines | 35 | 02/18/2009 | Kawagoe | JPN | Right | Right | 5' 10" | 215 lbs | $100,000 |
| Sekiguchi, Sadaharu | SP | Hanshin Tigers | 26 | 10/29/2018 | Tokyo | JPN | Left | Left | 6' 7" | 215 lbs | - |
| Shaw, Mike | LF | Free Agent | 43 | 04/08/2001 | Greencastle | USA | Left | Left | 6' 3" | 210 lbs | - |
| Shimizu, Yoichibei | SP | Chunichi Dragons | 26 | 08/20/2018 | Kawagoe | JPN | Right | Right | 5' 11" | 185 lbs | $900,000 |
| Shinoda, Naonobu | RF | Chiba Marines | 37 | 11/15/2006 | Nabari | JPN | Left | Left | 6' 2" | 195 lbs | $176,000 |
| Shinoda, Yoshimochi | 2B | Yokohama BayStars | 22 | 03/29/2022 | Kyoto | JPN | Right | Right | 5' 10" | 170 lbs | - |
| Shiraishi, Toichi | MR | Hanshin Tigers | 22 | 10/09/2022 | Osaka | JPN | Right | Right | 6' 1" | 185 lbs | $100,000 |
| Sierra, Francisco | 3B | Saitama Lions | 39 | 11/21/2004 | Lake Jackson | USA | Right | Right | 6' 0" | 205 lbs | $4,400,000 |
| Sizemore, James | 3B | Yomiuri Giants | 32 | 01/25/2012 | Conning Towers-Nautilus Park | USA | Right | Right | 6' 0" | 185 lbs | - |
| Soma, Naonobu | 2B | Hanshin Tigers | 35 | 09/12/2009 | Uchinada | JPN | Right | Right | 6' 2" | 245 lbs | $160,000 |
| Song, Kyung-bok | SP | Free Agent | 19 | 07/11/2025 | Kunpo | KOR | Right | Right | 6' 2" | 190 lbs | - |
| Stevens, Jeff | MR | Fukuoka Hawks | 33 | 02/17/2011 | Columbus | USA | Right | Right | 5' 8" | 170 lbs | - |
| Stewart, Deron | MR | Fukuoka Hawks | 28 | 02/01/2016 | Houston | USA | Switch | Right | 6' 6" | 220 lbs | - |
| Stokell, Charlie | SS | Hanshin Tigers | 36 | 01/21/2008 | Milton Keynes | ENG | Right | Right | 6' 0" | 195 lbs | $484,000 |
| Sugano, Takehide | RF | Fukuoka Hawks | 36 | 02/26/2008 | Tokyo | JPN | Left | Left | 6' 4" | 195 lbs | $100,000 |
| Sugiyama, Toshiki | CF | Yokohama BayStars | 21 | 06/10/2023 | Nagoya | JPN | Right | Right | 5' 11" | 180 lbs | - |
| Suzuki, Kenkichi | SS | Hanshin Tigers | 28 | 05/31/2016 | Osaka | JPN | Right | Right | 6' 2" | 205 lbs | - |
| Suzuki, Michihiro | SP | Chunichi Dragons | 24 | 12/04/2019 | Otake | JPN | Right | Right | 6' 0" | 195 lbs | - |
| Suzuki, Shichirobei | CF | Saitama Lions | 20 | 01/20/2024 | Yokohama | JPN | Switch | Right | 6' 2" | 185 lbs | - |
| Swift, Artie | MR | Yokohama BayStars | 33 | 08/28/2011 | Gurnee | USA | Right | Right | 6' 1" | 215 lbs | $350,000 |
