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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | ERA | YEAR | Open Career Leaderboard |
|---|---|---|---|---|
| 1 | José Cortéz | 1.364 | 2024 | |
| 2 | Juan Pineda | 1.463 | 2021 | |
| 3 | Mario González | 1.609 | 2038 | |
| 4 | Felipe Ferreira | 1.714 | 2019 | |
| 5 | Alonso Aguilar | 1.744 | 2016 | |
| 6 | Pedro Salas | 1.764 | 2018 | |
| 7 | Omar Zumaya | 1.813 | 2019 | |
| 8 | Rafael Rodríguez | 1.887 | 2026 | |
| 9 | Rafael Rodríguez | 1.943 | 2029 | |
| 9 | José Cortéz | 1.943 | 2022 | |
| 11 | Augusto Gonzáles | 1.980 | 2022 | |
| 12 | José Luján | 1.986 | 2018 | |
| 13 | Juan Pineda | 2.016 | 2017 | |
| 14 | Felipe Ferreira | 2.044 | 2018 | |
| 15 | Juan Pineda | 2.077 | 2020 | |
| 16 | Omar Zumaya | 2.085 | 2020 | |
| 17 | Jorge Martínez | 2.105 | 2015 | |
| 18 | Jorge Cervantes | 2.107 | 2027 | |
| 19 | Luis Castillo | 2.114 | 2024 | |
| 20 | Rafael Rodríguez | 2.119 | 2028 | |
| 20 | Jorge Castillo# | 2.119 | 2034 | |
| 22 | Ángel Solís | 2.134 | 2016 | |
| 23 | Rafael Rodríguez | 2.143 | 2024 | |
| 24 | Augusto Juárez | 2.163 | 2018 | |
| 25 | Roberto Martínez# | 2.176 | 2043 | |
| 26 | Alonso Aguilar | 2.179 | 2018 | |
| 27 | Albert Corona# | 2.185 | 2031 | |
| 28 | Rafael Rodríguez | 2.201 | 2025 | |
| 29 | Juan Pineda | 2.231 | 2018 | |
| 30 | Víctor Martínez | 2.242 | 2018 | |
| 31 | Alejandro Miranda | 2.243 | 2026 | |
| 32 | Guillermo Negrón# | 2.244 | 2029 | |
| 33 | António Sosa | 2.250 | 2028 | |
| 33 | Víctor Martínez | 2.250 | 2014 | |
| 35 | Álex Fuentes# | 2.255 | 2036 | |
| 36 | Félix Estrada# | 2.258 | 2038 | |
| 37 | José Pérez# | 2.293 | 2032 | |
| 38 | Carlos García | 2.296 | 2019 | |
| 39 | Emílio Soto# | 2.303 | 2035 | |
| 40 | Guillermo Negrón# | 2.304 | 2031 | |
| 41 | Félix Estrada# | 2.330 | 2035 | |
| 42 | José Zúñiga# | 2.335 | 2032 | |
| 43 | Rafael Rodríguez | 2.348 | 2022 | |
| 44 | Omar Zumaya | 2.354 | 2021 | |
| 45 | Mario González | 2.356 | 2037 | |
| 46 | Emílio Soto# | 2.364 | 2033 | |
| 47 | Rafael Rodríguez | 2.371 | 2027 | |
| 48 | Alberto Díaz | 2.373 | 2027 | |
| 49 | Carlos García | 2.389 | 2024 | |
| 50 | Felipe Canó | 2.400 | 2014 | |
| 51 | Raúl Bernal | 2.402 | 2021 | |
| 52 | Jesús Sánchez | 2.403 | 2028 | |
| 53 | Alonso Aguilar | 2.405 | 2015 | |
| 54 | José Cortéz | 2.406 | 2023 | |
| 54 | Ángel Sevares# | 2.406 | 2040 | |
| 56 | Víctor Martínez | 2.423 | 2020 | |
| 57 | Juan Quiñonez | 2.426 | 2032 | |
| 58 | Alberto Vázquez | 2.431 | 2025 | |
| 59 | Raúl Bernal | 2.432 | 2019 | |
| 60 | Jaime Meza | 2.433 | 2017 | |
| 61 | Rafael Rodríguez | 2.436 | 2023 | |
| 62 | José Olivas# | 2.449 | 2042 | |
| 63 | Rafael Rodríguez | 2.455 | 2021 | |
| 64 | Tony Garanzuay | 2.463 | 2034 | |
| 65 | Juan Hernández | 2.473 | 2018 | |
| 66 | Raúl Márquez | 2.483 | 2019 | |
| 67 | Juan Pineda | 2.497 | 2024 | |
| 68 | Edgar Martínez# | 2.498 | 2029 | |
| 69 | Raúl Bernal | 2.502 | 2022 | |
| 70 | José Zúñiga# | 2.512 | 2028 | |
| 71 | Mario González | 2.515 | 2027 | |
| 72 | Mario González | 2.531 | 2034 | |
| 72 | Juan Pineda | 2.531 | 2028 | |
| 74 | Omar Zumaya | 2.538 | 2017 | |
| 75 | Felipe Canó | 2.547 | 2015 | |
| 76 | José Zúñiga# | 2.551 | 2027 | |
| 77 | Víctor Martínez | 2.562 | 2015 | |
| 78 | Júlio Rodríguez# | 2.563 | 2040 | |
| 79 | Raúl Márquez | 2.565 | 2027 | |
| 79 | Pancho Zumaya | 2.565 | 2014 | |
| 81 | Javier Banda | 2.571 | 2025 | |
| 82 | Pedro Tobías | 2.583 | 2024 | |
| 83 | Rafael Rodríguez | 2.606 | 2033 | |
| 84 | Wilson Cruz | 2.607 | 2031 | |
| 85 | Rafael Rodríguez | 2.609 | 2031 | |
| 86 | Tomás Ramírez | 2.610 | 2019 | |
| 87 | José Rojas | 2.615 | 2028 | |
| 88 | José Zúñiga# | 2.623 | 2029 | |
| 89 | José Zúñiga# | 2.628 | 2026 | |
| 90 | Omar Zumaya | 2.632 | 2018 | |
| 90 | Sergio Domínguez | 2.632 | 2033 | |
| 92 | José Rojas | 2.634 | 2027 | |
| 92 | Miguel Muñóz# | 2.634 | 2039 | |
| 94 | Javier Banda | 2.636 | 2026 | |
| 95 | Alejandro Miranda | 2.641 | 2027 | |
| 96 | Juan Morales# | 2.644 | 2042 | |
| 97 | Raúl Díaz# | 2.646 | 2030 | |
| 98 | António Sosa | 2.653 | 2029 | |
| 99 | Ramiro Lozano | 2.654 | 2021 | |
| 100 | Augusto Juárez | 2.666 | 2017 |
