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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Lúcio Chávez# | 248 | 2025-2043 | |
| 2 | Guillermo Elías | 234 | 2021-2035 | |
| 3 | Edgar Martínez# | 225 | 2026-2042 | |
| 4 | Jorge Morales# | 212 | 2029-2043 | |
| 5 | Jesús Sánchez | 182 | 2021-2039 | |
| 6 | Félix Martínez# | 166 | 2031-2042 | |
| 7 | Enrique Olivo | 165 | 2014-2030 | |
| 8 | Juan Colomo# | 163 | 2031-2043 | |
| 9 | Jorge Pinto | 161 | 2023-2039 | |
| 10 | Miguel León | 158 | 2014-2026 | |
| 11 | Raúl Martínez | 156 | 2021-2035 | |
| 12 | Luis Meléndez | 155 | 2014-2031 | |
| 13 | Augusto Flores | 154 | 2014-2025 | |
| 14 | Félix Fuantes | 153 | 2016-2027 | |
| 15 | Héctor Mejía | 152 | 2014-2026 | |
| 15 | José Quiñones | 152 | 2023-2036 | |
| 17 | Alberto Vázquez | 149 | 2014-2027 | |
| 18 | Félix Estrada# | 148 | 2028-2043 | |
| 18 | Jesús Rodríguez# | 148 | 2034-2043 | |
| 20 | Jesús Córdova# | 145 | 2035-2043 | |
| 21 | Juan González | 144 | 2022-2042 | |
| 21 | Manuel Llatas | 144 | 2021-2039 | |
| 23 | Rubén Martínez | 142 | 2020-2034 | |
| 24 | Carlos García | 141 | 2014-2028 | |
| 25 | Juan Cortéz# | 139 | 2025-2041 | |
| 26 | Ramiro Lozano | 137 | 2019-2035 | |
| 27 | Juan Reyes# | 136 | 2032-2043 | |
| 28 | Juan Quiñonez | 135 | 2029-2036 | |
| 29 | Mario González | 133 | 2023-2042 | |
| 30 | Jesús García | 132 | 2023-2036 | |
| 31 | Andrés Sánchez | 129 | 2022-2035 | |
| 32 | Sergio Domínguez | 128 | 2025-2037 | |
| 32 | Jorge Ramírez# | 128 | 2033-2043 | |
| 34 | José Díaz | 126 | 2014-2026 | |
| 35 | Francisco De La Garza# | 124 | 2025-2043 | |
| 35 | Víctor Martínez | 124 | 2014-2029 | |
| 35 | José Olivas# | 124 | 2037-2043 | |
| 38 | Jesús Sánchez | 123 | 2028-2038 | |
| 39 | Bernardo Reynoso# | 121 | 2032-2043 | |
| 40 | Manny López# | 120 | 2034-2043 | |
| 41 | Ramón García | 119 | 2019-2033 | |
| 42 | Omar Zumaya | 118 | 2017-2033 | |
| 43 | Manny González | 117 | 2014-2025 | |
| 44 | Raúl Márquez | 116 | 2017-2029 | |
| 44 | Alejandro Miranda | 116 | 2015-2034 | |
| 46 | Ramón Martínez | 115 | 2014-2025 | |
| 46 | António Vázquez | 115 | 2025-2036 | |
| 48 | Sergio Valenzuela# | 111 | 2030-2041 | |
| 49 | Felipe Ferreira | 110 | 2014-2024 | |
| 49 | Pedro Ortíz | 110 | 2022-2036 | |
| 49 | Edgardo Rivera | 110 | 2014-2031 | |
| 52 | Orlando García# | 105 | 2028-2041 | |
| 53 | Augusto Juárez | 104 | 2014-2021 | |
| 53 | Tomás Ramírez | 104 | 2014-2026 | |
| 55 | Luis Corona# | 103 | 2034-2043 | |
| 55 | Luis Pereira# | 103 | 2035-2043 | |
| 57 | Augusto Gonzáles | 102 | 2019-2033 | |
| 57 | Gonzalo Martínez# | 102 | 2034-2043 | |
| 57 | Juan Pineda | 102 | 2015-2029 | |
| 60 | Juan Pantoja | 101 | 2014-2030 | |
| 61 | Luis González | 99 | 2014-2025 | |
| 62 | Rafael Rodríguez | 97 | 2021-2038 | |
| 63 | Marcos Fernández# | 96 | 2034-2043 | |
| 64 | Pedro Rodríguez# | 95 | 2032-2042 | |
| 65 | Andrés Reyes | 94 | 2025-2035 | |
| 65 | Ángel Solís | 94 | 2014-2026 | |
| 65 | Luis Torres | 94 | 2014-2025 | |
| 68 | David Tovar# | 92 | 2028-2043 | |
| 69 | José Flores# | 89 | 2031-2043 | |
| 70 | Francisco Medina# | 87 | 2035-2043 | |
| 70 | Emílio Soto# | 87 | 2029-2043 | |
| 72 | Raúl Díaz# | 85 | 2026-2040 | |
| 73 | Emílio Otero# | 84 | 2035-2043 | |
| 73 | José Rojas | 84 | 2022-2035 | |
| 73 | Pedro Tobías | 84 | 2014-2028 | |
| 76 | Roberto Vela# | 83 | 2037-2043 | |
| 77 | Alberto Díaz | 82 | 2022-2030 | |
| 77 | León Flores# | 82 | 2030-2039 | |
| 77 | Alfredo Mendoza# | 82 | 2037-2043 | |
| 77 | Francisco Rodríguez | 82 | 2025-2037 | |
| 77 | Gilberto Sánchez# | 82 | 2033-2043 | |
| 82 | Ricardo Dueñas | 80 | 2014-2024 | |
| 83 | Héctor Cruz | 79 | 2022-2033 | |
| 83 | António Santana# | 79 | 2035-2043 | |
| 85 | José Pérez# | 78 | 2030-2043 | |
| 86 | José Cortéz | 77 | 2018-2039 | |
| 86 | José Zúñiga# | 77 | 2018-2039 | |
| 88 | Andrés González# | 76 | 2028-2043 | |
| 88 | Jesús Pérez# | 76 | 2028-2033 | |
| 90 | Alberto Guerrero# | 75 | 2036-2043 | |
| 90 | Alonso Martínez | 75 | 2028-2040 | |
| 92 | Fernando Rangel | 74 | 2014-2025 | |
| 93 | Rodrigo Barrón# | 73 | 2038-2043 | |
| 93 | Ángel Luna# | 73 | 2034-2043 | |
| 93 | Iván Toledo# | 73 | 2034-2043 | |
| 96 | Fidel Cannilo | 72 | 2014-2020 | |
| 96 | Pablo Rivera | 72 | 2014-2020 | |
| 96 | Carlos Solís | 72 | 2014-2021 | |
| 99 | Valentín Fernández# | 70 | 2028-2042 | |
| 99 | Jaime Meza | 70 | 2014-2022 |
