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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Leonardo Cota# | 314 | 2026-2043 | |
| 2 | Víctor Díaz | 248 | 2021-2040 | |
| 2 | Jorge Hernández# | 248 | 2026-2043 | |
| 4 | José Calderón | 240 | 2014-2029 | |
| 5 | Luis Sáenz | 232 | 2019-2036 | |
| 6 | Ricardo Gutiérrez# | 221 | 2030-2043 | |
| 7 | Fernando Crespo# | 218 | 2028-2043 | |
| 8 | Julián Rodríguez | 210 | 2024-2041 | |
| 9 | Juan Silva | 209 | 2025-2039 | |
| 10 | Luis Solíz | 206 | 2015-2039 | |
| 11 | Pedro Ramírez | 202 | 2014-2027 | |
| 12 | Pedro Hernández | 196 | 2019-2040 | |
| 13 | José Peña# | 179 | 2032-2043 | |
| 14 | Ramón Candelalia | 178 | 2014-2027 | |
| 15 | Cristo Colomo | 172 | 2021-2042 | |
| 15 | Fernando Ferrer | 172 | 2014-2024 | |
| 17 | Tony Rojas# | 165 | 2030-2043 | |
| 18 | Ramón Fernández# | 164 | 2022-2043 | |
| 19 | Raúl Pacheco | 154 | 2018-2034 | |
| 20 | Juan Rosado | 150 | 2014-2025 | |
| 21 | Arturo Sánchez | 149 | 2019-2042 | |
| 22 | António Mojica# | 142 | 2035-2043 | |
| 23 | Francisco Cavazos | 141 | 2026-2041 | |
| 23 | Luis Ortíz# | 141 | 2035-2043 | |
| 25 | Fernando Rodríguez | 139 | 2019-2032 | |
| 26 | Roberto Hernández# | 136 | 2025-2043 | |
| 27 | Jesús Gonzáles# | 134 | 2029-2043 | |
| 28 | Carlos Sánchez# | 133 | 2031-2043 | |
| 29 | Carlos Reyes | 131 | 2024-2039 | |
| 30 | José García | 129 | 2014-2024 | |
| 30 | Júlio Quintana | 129 | 2014-2023 | |
| 32 | Gabriel Valle | 126 | 2014-2023 | |
| 32 | José Zumaya# | 126 | 2021-2036 | |
| 34 | Alfredo Gómez | 125 | 2017-2037 | |
| 34 | Jesús Negrón# | 125 | 2027-2043 | |
| 36 | Júlio Morín | 124 | 2024-2042 | |
| 37 | Aurelio Duarte | 122 | 2014-2026 | |
| 38 | Dani Valadez | 121 | 2021-2030 | |
| 39 | Jesús Silva# | 119 | 2029-2040 | |
| 40 | Bartolo Barajas# | 117 | 2032-2043 | |
| 41 | Jorge Márquez | 115 | 2014-2024 | |
| 41 | Roberto Rodríguez# | 115 | 2033-2043 | |
| 43 | Tomás Díaz | 114 | 2022-2039 | |
| 44 | Juan Jiménez | 113 | 2019-2038 | |
| 45 | Enrique Cuellar | 112 | 2014-2023 | |
| 46 | Alejandro Rodríguez# | 109 | 2035-2040 | |
| 47 | Juan Delgado | 108 | 2014-2028 | |
| 47 | Martín Reyes | 108 | 2019-2037 | |
| 49 | Augusto Soto | 106 | 2028-2040 | |
| 50 | Ángel Villegas | 105 | 2016-2031 | |
| 51 | Jesús González | 104 | 2022-2030 | |
| 51 | José Pacheco | 104 | 2021-2038 | |
| 51 | Luis Peña | 104 | 2023-2036 | |
| 51 | Ricardo Quintero# | 104 | 2037-2043 | |
| 55 | Vicente Espinoza | 103 | 2017-2032 | |
| 55 | Mario Gómez | 103 | 2014-2025 | |
| 55 | Javier Gonzáles# | 103 | 2030-2043 | |
| 55 | Ricardo Pérez | 103 | 2021-2036 | |
| 59 | Felipe Díaz# | 101 | 2029-2043 | |
| 60 | Félix Medina# | 100 | 2036-2043 | |
| 61 | Francisco Torres# | 99 | 2028-2034 | |
| 62 | Rafael Benítez# | 97 | 2031-2040 | |
| 63 | Bernardo Cruz | 96 | 2021-2040 | |
| 64 | Paco Delgado | 94 | 2014-2019 | |
| 65 | Alonso Ferreira | 92 | 2014-2028 | |
| 66 | David Valdés | 90 | 2014-2022 | |
| 67 | Vicente Contreras | 88 | 2021-2039 | |
| 67 | Ricardo Soto | 88 | 2022-2030 | |
| 69 | Ismael Rodríguez | 87 | 2023-2030 | |
| 70 | Rafael Gonzáles | 85 | 2024-2033 | |
| 70 | Francisco Luna | 85 | 2029-2039 | |
| 70 | Alberto Ojeda | 85 | 2014-2023 | |
| 70 | Álex Sánchez | 85 | 2014-2023 | |
| 74 | Pedro Salinas# | 84 | 2037-2043 | |
| 75 | Luis Crus | 79 | 2014-2025 | |
| 75 | David Reynoso | 79 | 2014-2022 | |
| 75 | Ángel Rodríguez# | 79 | 2037-2043 | |
| 78 | Enrique González | 78 | 2019-2032 | |
| 79 | Cristo Eilzando# | 77 | 2034-2043 | |
| 79 | Roberto Rodríguez# | 77 | 2029-2043 | |
| 79 | Francisco Vélez# | 77 | 2038-2043 | |
| 82 | Gustavo Rojas | 76 | 2028-2042 | |
| 82 | Raúl Rosário# | 76 | 2038-2043 | |
| 84 | Carlos Garza# | 75 | 2032-2043 | |
| 85 | Claudio Pérez# | 73 | 2028-2040 | |
| 86 | Jaime Jiménez# | 72 | 2031-2043 | |
| 87 | César Herrera | 71 | 2014-2024 | |
| 88 | Tony Adame | 70 | 2025-2039 | |
| 88 | Alberto Casillas | 70 | 2014-2030 | |
| 88 | José Flores# | 70 | 2028-2042 | |
| 91 | Manuel Berrios | 69 | 2014-2022 | |
| 92 | Ramón Bernal | 68 | 2019-2035 | |
| 92 | Jaime López | 68 | 2014-2022 | |
| 94 | Alberto Marmolejo | 67 | 2020-2038 | |
| 94 | Juan Jose Salazar# | 67 | 2035-2040 | |
| 96 | José Hernández | 65 | 2019-2023 | |
| 96 | Ramón Martínez | 65 | 2014-2023 | |
| 98 | Mauro Cabral | 63 | 2014-2023 | |
| 98 | Ricardo Juárez | 63 | 2028-2034 | |
| 98 | Luis Valéncia | 63 | 2029-2039 |
