| Date | Player | Home Runs | |
| 04/14/1994 | Dean Boughey | 3 Home Runs, 3 for 5, 6 RBI versus Avondale while playing for St. Louis | |
| 06/28/2013 | Phillip Ward | 3 Home Runs, 4 for 4, 5 RBI versus Saint Petersburg while playing for Reagan | |
| 08/04/2013 | Fred Williams | 3 Home Runs, 4 for 4, 5 RBI versus Avondale while playing for Reagan | |
| 08/02/2016 | Mike Mason | 3 Home Runs, 3 for 4, 4 RBI versus Lubbock while playing for Lodi | |
| 08/07/2016 | Pepe Jiménez | 3 Home Runs, 3 for 5, 7 RBI versus Guanajuato while playing for Reagan | |
| 04/20/2017 | Emílio Pérez | 3 Home Runs, 4 for 4, 5 RBI versus Rochester while playing for Bakersfield | |
| 04/22/2017 | Tetsuyuki Yamamoto | 4 Home Runs, 4 for 5, 7 RBI versus Orinda while playing for Modesto | |
| 04/26/2017 | Chad Turpin | 3 Home Runs, 3 for 5, 11 RBI versus Whisper Walk while playing for Modesto | |
| 05/11/2017 | Ron Henry | 3 Home Runs, 3 for 5, 5 RBI versus Vancouver while playing for Laredo | |
| 05/21/2017 | Randy Johnson | 3 Home Runs, 3 for 6, 5 RBI versus Whisper Walk while playing for Lubbock | |
| 05/29/2017 | Víctor Hernández | 3 Home Runs, 3 for 5, 7 RBI versus Rochester while playing for Saint Petersburg | |
| 06/11/2017 | Jerry Barnett | 3 Home Runs, 3 for 4, 4 RBI versus Rochester while playing for Vancouver | |
| 06/13/2017 | Mauro Canó | 3 Home Runs, 3 for 6, 5 RBI versus Rochester while playing for Laredo | |
| 06/29/2017 | Orlando Díaz | 3 Home Runs, 3 for 5, 9 RBI versus Stottville while playing for Lodi | |
| 07/03/2017 | Gerardo Berroa | 3 Home Runs, 3 for 3, 6 RBI versus Reagan while playing for Vancouver | |
| 07/23/2017 | George Johnson | 3 Home Runs, 3 for 5, 6 RBI versus Saint Petersburg while playing for Potosi | |
| 07/29/2017 | Simon Rainaducci | 3 Home Runs, 3 for 5, 7 RBI versus Halifax while playing for Rochester | |
| 08/04/2018 | Rubén Castro | 3 Home Runs, 4 for 4, 6 RBI versus Reagan while playing for Halifax | |
| 04/15/2020 | Emerson Sullivan | 3 Home Runs, 4 for 5, 5 RBI versus Orinda while playing for Rhinelander | |
| 05/23/2021 | Jeff Hubbard | 3 Home Runs, 3 for 5, 12 RBI versus Rochester while playing for Birmingham | |
