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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Orlando Sánchez | 287 | 2022-2038 | |
| 2 | Manuel Morales | 255 | 2027-2038 | |
| 3 | Vincenzio Turina | 254 | 2031-2045 | |
| 4 | Alejandro Ruíz | 234 | 2047-2062 | |
| 5 | Todd Poole | 232 | 2038-2049 | |
| 6 | Joaquín Gonzáles | 207 | 2017-2028 | |
| 7 | Tyler Bryant | 204 | 2060-2070 | |
| 8 | Chili Barber | 192 | 2035-2044 | |
| 9 | Mark Inman | 188 | 1999-2009 | |
| 10 | Ruben Alonso | 187 | 2058-2067 | |
| 11 | Freddy Ibarra | 183 | 2056-2069 | |
| 12 | Franklin Dunn | 179 | 2023-2040 | |
| 13 | Matt Keys | 176 | 2049-2059 | |
| 14 | Mang Baal | 171 | 2051-2065 | |
| 15 | Dairon Alvarez# | 169 | 2066-2075 | |
| 15 | Jesús Cortés | 169 | 2024-2036 | |
| 17 | Kevin Gaudet | 168 | 2034-2046 | |
| 18 | Martín Benavides | 167 | 2028-2041 | |
| 19 | Jonah Cooper | 165 | 2026-2036 | |
| 20 | Cory Dring | 163 | 2023-2032 | |
| 21 | Judite Oliva | 162 | 2001-2012 | |
| 22 | Rubén Castro | 160 | 2020-2026 | |
| 22 | Alberto Marin | 160 | 2061-2075 | |
| 24 | Jason McNeil | 159 | 2020-2031 | |
| 25 | Montrell Squillino | 158 | 2046-2056 | |
| 26 | Sergio Horta | 157 | 2048-2063 | |
| 27 | Randy Wakeham | 156 | 2036-2047 | |
| 27 | Ken Yamaguchi | 156 | 2047-2060 | |
| 29 | Luis Rocha | 155 | 2013-2021 | |
| 30 | Rubén Alonso | 153 | 2033-2043 | |
| 31 | Alastair Ives | 152 | 2017-2024 | |
| 31 | Tatsuya Miyazaki | 152 | 2022-2032 | |
| 31 | David Rice | 152 | 2034-2043 | |
| 34 | Tom Petty | 149 | 2023-2030 | |
| 34 | Jesús Segura | 149 | 2038-2051 | |
| 34 | Héctor Vela | 149 | 2022-2035 | |
| 37 | Ángelo Benavides | 148 | 2014-2020 | |
| 37 | Angel Galicia | 148 | 2060-2066 | |
| 37 | Dan Hicks | 148 | 2025-2042 | |
| 40 | Chris Ford | 147 | 2035-2043 | |
| 40 | Tomás Sáenz | 147 | 2027-2039 | |
| 40 | Judson Wakeley | 147 | 2024-2038 | |
| 43 | Mike Jackson | 146 | 1995-2005 | |
| 43 | Moromao Jouda | 146 | 2049-2062 | |
| 45 | Hydrogen Bell | 145 | 2044-2059 | |
| 45 | Roberto Noriega | 145 | 2024-2038 | |
| 45 | Rolf Savoie | 145 | 2044-2061 | |
| 48 | Tim Balcom | 144 | 2026-2038 | |
| 48 | Sean Cheadle Jr.# | 144 | 2068-2075 | |
| 48 | Rafaello Dallavilla | 144 | 2048-2059 | |
| 51 | Carlos Fernández | 142 | 2026-2036 | |
| 51 | Kevin King | 142 | 2025-2034 | |
| 53 | Victor Albert | 139 | 2038-2048 | |
| 53 | Jeffery Edwards | 139 | 2030-2040 | |
| 53 | Cris López | 139 | 2031-2042 | |
| 53 | Ed Park | 139 | 2042-2056 | |
| 53 | Lucien Rochon | 139 | 2030-2037 | |
| 58 | Lucien Gagnon | 138 | 2026-2038 | |
| 59 | Tom Alston | 137 | 2027-2034 | |
| 59 | José Cabral | 137 | 2021-2035 | |
| 59 | Jack Clay | 137 | 2025-2035 | |
| 59 | Robby Hardey | 137 | 2057-2066 | |
| 63 | Les Maskery | 136 | 2056-2072 | |
| 64 | Branlis Dearmas | 135 | 2061-2072 | |
| 64 | Pete Floyd | 135 | 2021-2026 | |
| 64 | Yosvani Fonseca | 135 | 2056-2067 | |
| 64 | Dan Frazier | 135 | 2039-2049 | |
| 64 | Danny Gomez | 135 | 2058-2070 | |
| 64 | John Westover | 135 | 2056-2066 | |
| 70 | Ryan Balint | 134 | 2062-2069 | |
| 70 | Marty Ocampo | 134 | 2058-2067 | |
| 72 | Juan Ferreira | 133 | 2047-2065 | |
| 73 | Rob Wallace | 132 | 2025-2040 | |
| 74 | Jorge Mora | 131 | 2024-2035 | |
| 75 | MacKenzie MacFadzean | 130 | 2053-2067 | |
| 75 | Gerardo Velásquez | 130 | 2045-2062 | |
| 77 | Nick Lasater | 129 | 2029-2038 | |
| 78 | Ricardo Icamén | 128 | 2045-2062 | |
| 78 | Joe Robertson | 128 | 1994-2006 | |
| 80 | Chris Snowden | 127 | 2053-2066 | |
| 81 | Lorenzo Bray | 126 | 2024-2038 | |
| 81 | Brad Desautels | 126 | 2057-2067 | |
| 83 | Luther Dalmahoy | 125 | 2046-2062 | |
| 83 | Falco Keijzer | 125 | 2043-2057 | |
| 85 | Ben Baker | 124 | 2051-2063 | |
| 85 | Howard Larsen | 124 | 2042-2053 | |
| 85 | Steven Penn | 124 | 2012-2024 | |
| 85 | Ed Phillips | 124 | 2019-2025 | |
| 85 | Corey Platt | 124 | 2057-2069 | |
| 90 | Jason Less# | 123 | 2071-2074 | |
| 91 | Bartolo López | 122 | 2020-2026 | |
| 91 | Heiko Schulze | 122 | 2061-2072 | |
| 93 | António Cruz | 120 | 2007-2015 | |
| 93 | David Deaver | 120 | 2042-2052 | |
| 95 | Junji Matsuo | 119 | 2041-2047 | |
| 95 | Zier van Rooij | 119 | 2057-2063 | |
| 97 | Lance Norman | 118 | 2009-2015 | |
| 98 | Jonathan Key | 117 | 1997-2008 | |
| 98 | Steven Linn | 117 | 2063-2069 | |
| 98 | Carlos Ruíz | 117 | 2021-2030 |
